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Adaptogens are natural and artificial substances that improve the ability to overcome stressful conditions. Adaptogen concept was formulated in the mid-20th century, the prefix "ADAPTO" was derived from the generalized adaptation syndrome , which was then new discovery Theoretical Medicine . (Refer to the article adaptogen as pharmacological concept .)
Adaptogen is ideal pharmacological which differs from paracelsovského concept medicament long prevalent in Western (Euro-American) medical practice. Paracelsian paradigm does not distinguish between toxins and drugs, medication concept combines with a specific indication (main effect) and toxic effects of drugs known as "irrelevant". In contrast, an adaptogen must not be toxic or unilateral effects. Ideally the adaptogen not a major effect, but a stabilizing effect on the health of a complex of many physiological variables. (See also comparison and adaptogens paracelsovských drugs ).
The first natural adaptogens were described in the 50s of the 20th century, Russian scientists who received the so-called. Qi enhancing herbs, traditional Chinese medicine (TCM), rasayanas Ayurveda herbs and certain herbal tonics our pharmacopoeia. As a model of natural adaptogens served true ginseng. In addition to the stabilization of stress (hypothalamic-pituitary) axis at adaptogens examines protective effect on physiological systems (nervous, cardiovascular, liver, kidneys ...) and other health parameters, such as physical and mental performance, regeneration and healing, inflammation, pain and general immunity, in particular anti-cancer (see, e.g. effects of ginseng ). Details and references can be found on each page, which is at this site through the 250 ( site map here ). For historical reasons, here I emphasize the ginseng and its saponin ( panaxosidy ), see the list christensen2009gcb .