Allergy is an exaggerated acute response of the immune system to the presence of foreign antigens on the skin and mucous membranes. Under normal circumstances, acute rhinitis and urticaria are adaptive responses reducing the risk of infections , poisoning and parasites. However, unnatural allergy with an epidemic dimension appears in an urbanized society. It is manifested as hay fever, asthma, allergic urticaria, chronic skin allergies, allergic eczema, etc. The internal equivalent of allergy is anaphylaxis, the body's reaction to the presence of foreign antigen in the blood.
Prevention of allergy to prevent immunity naïve
From the above it follows that occasional "allergy" in the form of a rhyme is a natural reaction that confirms that our immune system works as it should. For me, such a reaction occurs mainly in contact with mold spores (moldy interiors), smoke and also cold. These are all situations where increased mucus production bleeds foreign particles from the airway and prevents a potentially fatal fungal infection of the airways. Increased cold mucus production in turn prevents "cold", that is, catching some of the frequent respiratory infections that are abundant during the cold period due to the relative lack of UV radiation. (Once, for example, tuberculosis.) But I'm a physically healthy person, and I grew up in a village where I've come into contact with all potential natural and dietary allergens since childhood. I am of the opinion that the most appropriate and, in fact, the only prevention of allergy in individuals with a healthy immune system is the prevention of immune naivety : that is, getting familiar with all harmless natural antigens from an early childhood. I'm counting on insect tropomyosin and other insect antigens that do not let your kids hang up - it's enough to make sure that you get through a chicken coop as it happens in the movie Come to the pilgrimage. (Do not forget that our ancestors went to the henhouse for a day, not a refrigerator!)
However, there are allergic patients who are caused by congenital hypersensitivity. Pathogen selection forces our immune system to diversity, so the immunity of different people works differently. Some of us respond unusually strongly to flying antigens (pollen, dust particles), so that the upper respiratory tract swelling and internal swelling like rhinitis occurs. This condition, called asthma, is not necessary to describe asthma sufferers in any way - it is an extremely unpleasant, life-threatening condition. Similar strong allergic conditions occur in some patients on the skin and digestive tract. In these patients, the importance of "second-line prevention" is important - ie, avoiding natural antigens, especially those with a strong allergic response. Such affected people have to create a hypoallergenic environment around them that is undesirable for normal teenagers. Even so, strong allergies tend to spread to other and other allergens - hence, heavy asthmatics must continually spray with an antihistamine. Immunosuppressive drugs and herbs with anti-inflammatory effects are also used in these patients.
Another note to today's environment is that urban smog contains highly reactive radicals that are generated by sunlight, for example, from nitrous oxides from automotive flue gases. The mixture of these radicals, smoke and organic fumes (poetically called smog) chemically modifies natural antigens (oxidation, alkylation, nitration, etc.), causing their increased irritation. A less experienced immune system can lead to hypersensitivity to the original, unmodified natural antigen (eg pollen). It follows that children nowadays should have immune experience with both unmodified natural antigens and industrially polluted environments - unless, of course, Czech scientists from the Institute for Human Improvement plan to replace the replacement of internal combustion engines with electric and industrial inventions in the next five years, toxic products will not be produced.
Treatment of allergy
I wrote about allergy prevention. However, it is necessary to treat already developed allergy, which is practiced in antihistamines and immunosuppressive drugs. Even less known is the fact that allergies also cushion some adaptogens, which are virtually non-existent in comparison with conventional drugs . (I could repeat the previous sentence for greater emphasis.) It goes without saying that people with developed allergies should avoid their allergens and create hypoallergenic environments as best they can to their needs.
Anti-allergic effects of ginseng
Ginsenosides Rb 1 , Rc , Rd , F 2 and Rh 1 inhibit the uptake of histamine and mauve leukotrienes from mast cells ( Christensen2009gcb ), thereby inhibiting the allergic response. Ginsenosides Rh 1 , Rh 2 and K are potent inhibitors of the skin anaphylactic reaction. Gssd. Rb 1 blocks the molecular mechanisms of allergy ( Liao2006eri ). In vivo ginseng extract suppresses skin allergy ( Samukawa2012rgi ), gssd. Rg 1 suppresses asthmatic response ( Jung2012rpg ) and allergic rhinitis ( Inoue2013krg ).
Other herbs with anti-allergic effects
- Baikal shishak was found to be effective against an allergic reaction ( Jung2012aes , Shin2014pes , Shin2014ssb , Bae2016bic ) and asthma ( Jang2012sii , Mabalirajan2013bra ). Its flavonoids reduce the activation of cells responsible for the allergic reaction - mast cells by acting on the pathway of the NF-κB promoter ( Hsieh2007bii , Shin2014pes ).
Other natural drugs with anti-allergic effects include shingle and glossy peril . The amount of herbs with anti-allergic effects is great and I do not know which ones are the strongest. For now, in this indication, I recommend ginseng and a personal visit to a doctor's office.