Chinese Koptis of the miraculous but dangerous Ranunculaceae are among the important herbs of the Czech Republic. The root is used ( rhizoma coptidis ). Koptis is a part of the antidiabetic herbal mixtures of TČM, the most important of which is the combination with the bayalis ( Liu2013aet , Zhen2011aec ), which may also include Rheum officinale and Bupleurum chinense ( Zhen2011aec ). Berberin and the total extract of Koptis root protected hippocampal cells from death ( Zhang2009btb ). It is a traditional remedy with a protective effect on the liver ( Lam2016hec ).
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