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I do not feel the effect of ginseng

Hello, I'm very glad you are creating such an interesting website. I would like to ask if I'm doing something wrong in preparing ginseng stuffing. I bought the slices of the 6-year-old ginseng TaiwanTCM Liang and started to prepare my infusion according to the enclosed instructions. For three days I made a spoon of 3 slices of root. I put the slices in a mug and pour it with boiling water and leave about 50 minutes to leaven. I do not feel like I'm feeling any change or some effects when using ginseng - more activity, less fatigue or something, so I would like to ask if I do not prepare poorly? Thank you. JJ

Dear JJ,

I originally did not want to write about the ginseng at all. But he can not be satisfied with his general understanding as a lifebuilder who heals everything and nothing. Ginseng and other adaptogens have specific, strong and long-lasting effects on the vascular, nervous and immune systems . These are not commonly known to our doctors or synthetic drug manufacturers. In medical journals, obviously rent articles (such as Messina2006hsf ) show that ginseng has "interactions" with drugs for thrombosis , diabetes , depression , etc. The aim of these articles is to conceal the fact that ginseng itself is a drug against thrombosis and diabetes. This, of course, is a breach of scientific and citation ethics that we are not accustomed to here. I try to remedy this by providing a full view of the relevant literature.

And now to use ginseng ...

Ginseng is preparing properly. Be sure that if the panaxoside levels in your blood or CSF were measured, a slowly increasing concentration would be measured in units of milligram / liter. Be sure these panaxosides bind to the appropriate nuclear and non-nuclear receptors of cells and act as they do.

The fact that you do not feel the effect can have several reasons:

1. Ginseng is used relatively briefly - effects come in three phases:

  • Short-term effects occur within hours and days. They are caused by direct interaction of panaxosides with non-nuclear receptors (receptors and enzymes in membrane and cytoplasm). This includes a vascular relaxing effect by allosteric enhancement of NO synthase 3 , effect on non-nuclear receptors in the brain, or cell membrane stabilizing effect. These effects are directly proportional to the current panaxoside levels in the blood.
  • Medium-term effects occur over days and weeks. These effects are due to panaxoside interactions with nuclear receptors and consequent change in gene expression. They come with a delay of several days with respect to the curve of panaxoside blood concentration, because gene expression involves mRNA transcription and translation of enzymes, which in humans lasts many hours. It takes a few days to establish a new level of protein that is affected by these nuclear receptors. Thus, for example, the anti-inflammatory effect of ginseng works by limiting the expression of cycloxygenase via the NF-κB nuclear receptor, the action of the glucocorticoid receptor, increased expression of NO synthase 3 in the blood vessels, etc. (Note: Panaxoside in NO synthase 3 acts both as an allosteric and an increased expression Of this enzyme.)
  • Long-term effects occur over weeks and months. The human organism is in the constant process of rebuilding, and when some parameters of cell behavior change, it may take many months for it to be reflected in the re-engineering of tissue systems. Ginseng may begin to improve capillary growth some days after you start taking it, but it takes months to improve your blood vessel organs. Although ginseng suppresses inflammation of the joints , it takes a long time before the damaged tissue recovers. Although ginseng reassures microglia in the brain and macrophages on the inner walls of the vessels, it takes a long time to do so by reducing neuronal death and a significant slowing down of atherosclerosis .

2. The dose of 3 slices per day may still not be high enough for subjective observation

Along with the effect on erection , the psychotropic effects are practically the only ones you have the chance to notice for a short time with ginseng. In the case of ginseng, it is actually possible to talk about happiness - they are adaptogens, such as glans , for which nothing can be learned subjectively.

However, the dose of 3 slices may not be high enough to distinguish ginseng from natural mood swings and performance. You know, many people feel the doses of more than 3 slices too high, so I did not want to recommend larger doses. To tell the truth, as far as I am concerned, I do not feel anything like myself with my 90kg live weight at a dose of 3 slices. In a dose of 15 slices, the effects (for me) are not overlooked, I recommend a high dose but I did not allow.

3. Ginseng is an adaptogen ...

The third reason is that ginseng as an adaptogen should not actually work or function in people beyond the burden. Its effect on the hypothalamic-pituitary (ie stress) axis will manifest itself especially when you are under stress. After all, ginseng is not a panacea or a miracle. TCM physicians tend to say that even ginseng is not for everyone. Perhaps you are completely well, you live in a balanced life in a relatively clean environment and you do not need ginseng. If this is the case, maintain a healthy lifestyle and trumps to save on the period of stress.

Regards,
-boris-

| 12.10.2010

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