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Cholinergic effects (memory protection)

Cholinergic model of memory impairment

Like depression, it can roughly be linked to serotonin and Parkinsonism with dopamine, the central acetylcholine system is associated with memory. The standard model of memory impairment in the research is the administration of a cholinergic antagonist of scopolamine. Substances whose memory effect is demonstrated on the model of scopolamine damage usually at least slightly help with the most common memory-damaging disease - Alzheimer's disease - although its real cause is the physical destruction of neurons by β-amyloid accumulation. The effects of their content on the central acetylcholine receptors and the biological pathways associated with them are therefore investigated in memory-protected adapogenic and nootropic effects.

Cholinergic Effects of Adaptogens - Impact on Memory

Many adaptogens have a protective effect on the CNS . This has also led to research into their impact on memory protection, which is linked to the cholinergic system.

Ginseng right to improve memory

Genuine Genital ( Nitta1995pge ), as well as American ginseng ( Sloley1999age ), regulate scopolamine disturbed learning in rats. This effect was specifically attributed to ginsenoside Rg1 ( Yamaguchi1995egi ) and ginsenoside Rb1 ( Benishin1991egr ), which also facilitates the uptake of acetylcholine from the hippocampus. According to Salim1997grr, ginsenoside Rb1 also expresses enzymes and acetylcholine transport transporters - choline acetyl transferase mRNA and the like. Inconsistent message about gssd. Rb 1 handles Yamaguchi1996egi , according to which memory protects gssd. Rg 1 and Re , but not gssd Rb 1 , R d , F 2 , R f , Rh 1 or 20-O-Glu-PPD . Gssd Rg 2 , Rg 3 , Compound K and protopanaxatriol aglycon reversibly block the neuronal acetylcholine nicotinic? 3? 4 receptor. ( Lee2003deb , Jeong2004sgr , Lee2009rlr ).

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