Astragalus membranaceus , a new propinquus, is a medicinal plant with cytoprotective, anti-inflammatory ( Li2016aia , Xin2015apa , Auyeung2016amr ) and antidiabetic effects. Fu2014rbc also protects the liver, acts anti-cancer and facilitates expectoration (expectorants). The active substances of the chicken are saponins (astragalosides), proteoglycan polysaccharides, flavonoids, proteins, amino acids, L-kanavanin etc. The most attention is paid to saponins and polysaccharides.
Kozinec is a part of TČM combination ťi-šen-i-ťi ( 洪 诚 韬 ), also containing Salvia miltiorrhiza , ginseng notoginseng and Dalbergia odorifera . This combination is used to treat ischemic heart disease and cardiovascular problems ( Chen2015qpc ).
I do not know how the information on anti-inflammatory effects is combined with the Denzler2016cpr study, in which there is a dynamic change in the level of cytokines, interleukins, interferon-γ, TNF-α and white blood cells accompanied by subjectively perceptible symptoms similar immune responses ( fatigue , weakness and headache ). In contrast to this information, according to Liu2016etc , the kozinec, on the contrary, is traditionally prescribed for fatigue.
- Kozinec is used in the treatment of diabetes ( Zhang2015bai , Lien2016itc ). It reduces glucose levels ( Tian2016eaa , Zhu2016aif ) and protects kidney and brain function in diabetic rats ( Li2011mcv , Dun2016eap , Xin2015apa , Yao2016aip ).
- It has anti-inflammatory and immunomodulatory ( Wang2016asi ) effects.
- Astragalosid IV acts against colon inflammation ( Cai2016aia , Tian2016apa ), which is one of the factors contributing to the effect of the colon against colon and rectal cancer ( Tin2007asi , Auyeung2009nae , Auyeung2010nhf , Auyeung2010asm , Law2012asd , Wang2014asm ).
- Saponins of the goat have apoptosis of HepG2 liver cancer cells. ( Auyeung2009asi )
- Kozinec acts against gastric cancer ( Wang2016aei , Auyeung2016amr ) and limits the invasiveness and angiogenesis of the stomach cancer cell line AGS ( Auyeung2012asm ).
- In accordance with its TČM indication, it has been effective against fatigue in patients with heart stroke ( Liu2016etc ).
An overview of the effects and properties of the major active ingredient of the astragaloside IV is Ren2013pea .