Astragalus membranaceus , a newer propinquus, is a healing plant with anti-inflammatory, cytoprotective and antidiabetic effects. It seems to protect the liver, it acts antitumorally and facilitates expectoration (it is expectorans). The active substances are saponins (astragalosides), proteoglycan polysaccharides, flavonoids, proteins, amino acids, L-kanavanine, etc. The most attention is paid to saponins and polysaccharides. An overview of the effects and properties of the major active ingredient of Astragaloside IV is Ren2013pea .
Immunomodulatory effects
Kozinec blanitý is a plant whose effect on immunity completely do not understand. On the one hand there are studies proving its anti-inflammatory effects ( Li2016aia , Xin2015apa , Auyeung2016amr , Wang2016asi ). On the other hand, there is a Denzler2016cpr study in which there is a dynamic change in the levels of cytokines, interleukins, interferon-γ, TNF-α and white blood cells, ie immune responses accompanied by subjective symptoms of immune responses ( fatigue , weakness and headache ). TČM, on the contrary, kozinec traditionally prescribed against fatigue ( Liu2016etc ). Assessing this plant requires practical experience that I do not have at the time of writing. I can only say that the kozinec is a classic miraculous herb of the TČM of a miraculous family (leguminous) whose adaptogenic qualities can be judged.
Cardiovascular effects
Kozinec is a part of the TCM combination of Ťi-šen-i-ťi ( 洪 诚 韬 ) for the treatment of ischemic heart disease and cardiovascular problems ( Chen2015qpc ). (This combination also contains reddish sage , notoginseng ginseng and parsley dalber .) The Liu2016etc study demonstrates its effect against fatigue in patients with heart stroke .
Antidiabetic and cytoprotective effects
Kozinec is used in the treatment of diabetes ( Zhang2015bai , Lien2016itc ). It reduces glucose levels ( Tian2016eaa , Zhu2016aif ) and protects kidney and brain function in diabetic rats ( Li2011mcv , Dun2016eap , Xin2015apa , Yao2016aip ). Fu2014rbc also protects the liver.
Anti-cancer effects
Astragaloside IV acts against colon inflammation ( Cai2016aia , Tian2016apa ) and therefore cancer. According to a number of studies, kozinec is suitable for colon and rectum cancer ( Tin2007asi , Auyeung2009nae , Auyeung2010nhf , Auyeung2010asm , Law2012asd , Wang2014asm ). Kozinec acts against gastric cancer ( Wang2016aei , Auyeung2016amr ) and limits the invasiveness and angiogenesis of the stomach cancer cell line AGS ( Auyeung2012asm ). According to Auyeung2009, the saponins of the goat had apoptosis of HepG2 liver cancer cells. This is not an irrefutable proof of its usefulness, but due to the experience of TCM it can be added to mixtures for supportive treatment of various types of cancer. It is also used in the prevention of cancer.