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Eleutherococcus senticosus (Rupr. & Maxim.) Maxim.)

(Also all-around, spiky, incorrectly "Siberian ginseng")

Eleuterokok ostnitý
Brekhman's drawing of eleuterokoka

Eleuterokok (the wrong Siberian ginseng ) was the first "ginseng" I had the opportunity to practice (it was during my trip to the Far East), which later led me to write this historical page about Eleutherococcus senticosus (Siberian Ginseng) . The site still has historical value, but it comes from a time when I was still the victim of two frequent mistakes - I considered the effects of ginseng to be scientifically inconclusive, and only on the basis of botanical affinity I considered that Siberian ginseng and ginseng genuine are almost identical to their Chemical composition. As a result, I was "helped" by the lack of information regarding only E. senticosus by paying back information from P. ginseng and P. quinquefolius . Somewhat apologizes to me for the fact that the same mistake was made by the famous Russian scientists at the beginning of the study of eleutherococcus.

Eleuterokok compared to the ginseng right.

Just like ginseng, eleuterokok is harmless. According to Medon1981het , LD 50 dried water extract of eleuterokoke was not able to determine (> 3g / kg) in mice.

The Medon1981het study, dating back to Brechman times, also demonstrates the hypoglycaemic effect of eleutherococcus. Brechman said that eleuterokok (even at athletes) is even more effective than ginseng. In general, eleutherococoks are considered to be less effective than ginseng, but today there is a significant number of studies demonstrating the possibility of its effect on stress and fatigue ( Deyama2001cpe , Cicero2004esg , Huang2011bfa , Panossian2009eea ). As with many other adaptogens, I would emphasize the need for proper dosing - one or two capsules a day is definitely not enough.

Unlike ginseng, other plants of the aralkovite family, including eleutherococcus, are woody shrubs, unlike their consistency for direct consumption. Eleutherococcus requires extraction. Medon1981het describes the preparation of the eleutrokrook extract with a 10 minute stirring of 100 g of powdered drug ( radix / lignum ) in 1000 ml of distilled water at 60 ° C. In this method 100 grams of eleutherococcus are obtained from 1 liter of a solution containing 1.6 grams of dissolved substances. These can be obtained by drying (lyophilization) as a powder extract. Therefore, if a manufacturer really filled the capsule, say 400mg of pure powder extract, we could talk about proper dosing. Such a product will not be so easy to see with us. What is offered in stores as eleuterokok, contains eleutherococcus extract, mostly in a small, totally ineffective quantity. In the former. USSR sells a relatively honest liquid eleutherococcus extract ( ?????????????? ), which would like to enjoy more than a few drops, as I did it.

Eleuterokok - an adaptogen whose discovery was inspired by ginseng

Eleutherococ, as an adaptogen, was discovered by Brechman by a systematic study of the aralcovite family ( Araliaceae ) to which his ginseng experience inspired him as an ergogenic agent. I would probably be biased now, but I would guess that Brechman ideally dreamed of discovering an even more effective adaptogen than ginseng. It turned out, however, that the genus genus is rare in the Aralkovite family, and the only other adaptogenic plant Brechman found in the Aralkovites was the eleutherococcus, which Brechman even began to claim to exceed ginseng in some aspects. This is a statement that many people have later argued for, but it is a reason for me to pay attention to eleutherococcus.

From a chemical point of view, ginseng and eleuterokok are completely different

The genus genus ( Panax ) is unique in the family Araliaceae . Its content, panaxosides , are not found in almost any other plant in addition to ginseng ( Gynostemma pentaphyllum ) contains about 0.5% ginseng panaxosides , whose leaves also contain a limited amount of panaxosides identical to those of ginseng. We know it today. It was not so clear in the days of Brechman - the whole idea of systematically searching the Aralkovite family was based on the assumption that the phylogenetic relationship with the ginseng will also manifest itself in chemical affinity. This assumption proved to be false - the discovery of eleutherococcus appears in this light as a happy coincidence that Brechman could equally well encounter when researching any other plant family.

Eleutherococcus content substances.

The phytochemical investigation of the plant begins with the isolation of the substance. He gave Eleutheroids the Eleutherous Eleutherocide, as exemplified by panaxosides / ginsenosides in ginseng. In the Davydov2000es review, the author expresses his dissatisfaction with this Brechman's choice ( which I have already written elsewhere ).

Eleutherococcus content does not match ginseng. In eleutherococcus, none of the ginseng panaxosides can be found. "Eleutherosides" are not specific to eleutherococcus, in other words, they have been previously described from common plants such as carrot, lilac, ivy, dsn.

Eleuteroside A = dacosterol

Eleutheroside B = syringin

Protects against radiation damage, immunomodulatory effect (referenced in Davydov2000es ).

Eleutheroside B1 = isofraxidine

Cytotoxic in mouse lymphocytic leukemia, cholagogue (referenced in Davydov 2000 ).

Eleuteroside B4 = sesamin

It reduces LDL cholesterol, anti-carcinogen, immunomodulatory, hepatoprotective (referenced in Davydov 2000 ).

Eleuteroside E = (-) syringesinol-4,4'-O-β-D-diglucoside = akantoside D

(Not printed)

Eleuteroside E1 = (-) syringesinol-O-β-D-monoglucoside

(Not printed)

Eleuteroside I, K, L, M

Oleanic glycosides

Betulinic acid

(Not printed)

Coffee acid

Antioxidant, cytoprotective, anti-tumor, anti- ductile ( arthritis urica ), antibacterial (referenced in Davydov2000es ).

Vitamin E

It is a well-known antioxidant vitamin.

Effects of eleuterokok

Eleutherococus has been investigated for many diseases and adaptation effects. It will take me a while to get all the sessions here, so far:

Sorry, but this article is not finished. Current, unfinished version does not express its final form.

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