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  1. Adaptogens
  2. Phytochemistry
  3. Ginsenosides / Panaxosides

42. ginsenoside 20 (R) -Rg3

ginsenoside 20 ( R ) -Rg3

It is the 20 ( R ) epimer of ginsenoside 20 ( S ) -Rg3

ginsenoside 20 (R) -Rg3

R 1 = -Glc 2-1 Glc
R2 = H

  • Gssd. 20 ( R ) Rg 3 as well as its 20 ( S ) epimer causes relaxation of intact endothelial porcine coronary artery strips following a previous contraction of 3 μM serotonin. ( Kim2006seg )
  • Gssd. 20 ( R ) Rg 3 , unlike the 20 ( S ) epimer, does not have an endothelium-independent relaxation effect on the blood vessel (coronary artery strips) contracted with 25 mM KCl. ( Kim2006seg )
  • Stereospecificity: gssd. 20 ( R ) Rg 3 does not show the same effects on Ca 2+ , K + and Na + ion channels as its 20 ( S ) epimer . However, both epimers inhibit the serotonin 5HT 3A receptor and the? 3? 4 nicotinic acetylcholine receptor. ( Jeong2004sgr )

| 2009 - 24.1.2018