Dear visitor, this is a machine-translated article. It makes perfect sense in its original language (Czech), and is fully backed by independent scientific literature. The translation, though, is far from perfect and takes patience and imagination, if you decide to read it.

Drobečková navigace

42. ginsenoside 20 (R) -Rg3

ginsenoside 20 ( R ) -Rg3

It is the 20 ( R ) epimer of ginsenoside 20 ( S ) -Rg3

ginsenoside 20 (R) -Rg3

R 1 = -Glc 2-1 Glc
R2 = H

  • Gssd. 20 ( R ) Rg 3 as well as its 20 ( S ) epimer causes relaxation of intact endothelial porcine coronary artery strips following a previous contraction of 3 μM serotonin. ( Kim2006seg )
  • Gssd. 20 ( R ) Rg 3 , unlike the 20 ( S ) epimer, does not have an endothelium-independent relaxation effect on the blood vessel (coronary artery strips) contracted with 25 mM KCl. ( Kim2006seg )
  • Stereospecificity: gssd. 20 ( R ) Rg 3 does not show the same effects on Ca 2+ , K + and Na + ion channels as its 20 ( S ) epimer . However, both epimers inhibit the serotonin 5HT 3A receptor and the? 3? 4 nicotinic acetylcholine receptor. ( Jeong2004sgr )

| 9.3.2009