Overview Chen2007chh offers a list of natural medicines and plants TCM with a potential effect against Parkinson's disease: ginseng , ginkgo (Ginkgo biloba) , knotweed (Polygonum) triptolid of Tripterygium wilfordii sharply poisonous oleander (Nerium indicum), lingzhi mushroom (Ganoderma lucidum) , huperzine (from Vranča, Huperzia), promising stefolidin (from corydalis Corydalis ambigua used in TCM) and tea polyphenols / catechins.
Ginseng generally protect neurons from dying, but ginsenoside Rd has been described specifically as a substance protecting dopaminergic neurons in cell culture in vitro experimental activated microglia lipopolysaccharides ( Lin2007gra ). The ginseng extract protected the dopaminergic neurons of rats and mice before causing parkinsonism to neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and its metabolite MPP + ( VanKampen2003nag ). According Watanabe1991epg prevent water extract of ginseng reducing the number of dopamine receptors in the brain of aging rats. Overall, the effects of ginseng against Parkinson's disease promising but little understood. Neuroprotective effect on memory ( Zhou2012nep , Aguirremoreno2011glr ) and specifically on dopaminergic neurons was found even lingzhi mushroom ( Ding2010gle ).