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Ginseng ( Panax ginseng CA Meyer )

(Also Ratsdream , All Ginseng / Genuine, Ginseng Asian / Chinese / Korean, or Ginseng only)

Plant and root Panax ginseng
Plant and root Panax ginseng

Genuine Genuine is the strongest strength of Asian medicine. It is the subject of extensive research and is rated as the most effective adaptogen - a "smart cure" .

Ginseng contains a mixture of several tens of unique, highly active ingredients , which make up more than 20% of the dried root weight. These are mainly triterpenoid saponins called panaxosides and ginsenosides , which are more than 182 in the genus Panax ( Christensen2009gcb ). Ginseng surpasses many common drugs and common stimulants (coffee, tea, nicotine, energy drinks, etc.). Its effect is slower, but it is long-term and beneficial in all aspects. To make full use of its preventive, curative and adaptive potential, it is important to use it properly.

Effects of ginseng right

Ginseng is so important because it works against diseases caused by the predominantly bad lifestyle - civilization diseases. Similar effects have ginseng American ( Chen2008cpe ). Diseases such as diabetes and metabolic syndrome ginseng treat causally-acting on the immune system and PPAR receptors, a common target of anti-diabetes drugs. The effects of ginseng can be divided into:

Cardiovascular effects - ginseng through the activation of NO synthase and other molecules reduces pressure in most types of hypertension and improves erection. The effect on gill capillary growth in turn improves wound healing and regeneration of tissues and vessels (including varicose veins and hemorrhoids). The ginseng also engages in atherosclerosis, which is now known to be not only a cholesterol problem, but also an immune and macrophage problem.

Nervous effects - Ginseng normalizes stress and protects the brain, slows down the weakening of mental functions (Alzheimer's, Parkinsonism, etc.). It causes mental activation and at the same time calms down. Protects neurons from dying (apoptosis) and calms microglia whose activity is responsible for both headaches and hangover.

Metabolic effects - Ginseng has significant anti-diabetic effects. Helps regulate blood glucose, regulates cholesterol, has a hypoglycaemic effect on diabetes of both types.

Immune effects - ginseng suppresses chronic inflammation, allergies and chronic pain (such as joints), is used in the treatment of tumors. Despite this, ginseng is not generally immunosuppressive. Improves immunity against influenza, viruses, cancer, and some bacteria. The effect of ginseng on immunity is the subject of intensive research. Here we can not mention the indication of ginseng dating back to the Brechman period: Treatment of radiation damage. This result of military research in the USSR has today strictly civilian application: Cancer patients are used to regenerate the immune system after chemotherapy and radiotherapy. In radiation damage, ginseng is considered to be the best existing drug at all ( Yonezawa1976rri , Takeda1982rri , Yonezawa1981rri ).

How Does Ginseng Have So Many Effects?

Many diseases combine the hidden common cause of origin. If ginseng acts on this cause, it seems to have treated several diseases at the same time. A typical example of this situation is the action of ginseng against autoimmune damage, which is responsible for rheumatic joint pain, thyroid inflammation, type I diabetes , neurodegenerative diseases, lupus, psoriasis and dozens of other diseases.

The list of effects of ginseng can only create distrust of its length. Even scholarly scholars sometimes feel the need to apologize for the extent of the effects of ginseng ( Attele1999gp , Davydov2000es ). A large number of seemingly unrelated indications of ginseng is a result of modulation effects of ginseng on key biochemical signaling pathways - ginseng panaxosides interact with a relatively small number of nuclear and membrane receptors that alter gene expression throughout the body and play a role in many different diseases:

Unscientific TCE says ginseng strengthens qi , affects the meridians of the heart, spleen and lungs, and thus increases the production of body juices that are thirsty, calm and intelligent, and that ginseng heals crash due to lack of chi , fatigue , loss of appetite, diarrhea, dyspnea , Weak pulse, sweating, diabetes , fever illness, forgetfulness , insomnia, and impotence (both Chen2008cpe statements ). Scientific reports present the effects of ginseng in a different order (cf. Christensen2009gcb , Attele1999gp , Choi2008bcp , Davydov2000es ).

How Does Ginseng Do Not Have Harmful Effects?

The secret of the extraordinary success of ginseng as a " smart medicine " is that its ginseng content affects the physiological parameters of our organism neutral - they have the ability to help the organism stabilize these parameters (ie increase or decrease as needed). This ability is based on the adverse effect of ginseng active substances .

Despite the extraordinary amount of effects, however, ginseng surprisingly has almost no contraindications (with the exception of some acute infectious diseases where antibacterial immunity weakens), has no undesirable interactions with conventional drugs and is not a prohibited substance for athletes . Although it acts against inflammation, allergies and autoimmunity, ginseng is not immunosuppressive .

From an evolutionary point of view, the extraordinaryness of ginseng is not satisfactorily explained

Ginseng seems to have no evolutionary reason to create human beneficial substances. Ginseng is not genetically domesticated so its healing effects can not be explained by artificial selection. There is a possibility that the effect of ginseng on human health is purely accidental. Another hypothesis commented by Davidov ( Davydov2000es ) regarding Siberian ginseng (eleuterokokem) is that effective saponins are a kind of chemical service system useful for the plant itself, which by the same token preserves some of its usefulness even in the human body. Thanks to its extraordinaryness, the ginseng is enveloped by many superstitions and obscenities.

Compared to commercial drugs, ginseng is more than good

To fully understand the comparison of ginseng with conventional drugs, we first need to realize that over a huge number of different names 80% of the tablets are used on a small number of pathways . Ginseng covers several popular drug mechanisms: inhibition of cycloxygenase, anti-stress effects, pressure reduction, potency enhancement, antioxidant and cytoprotective effects. Modulation of gene expression achieves ginseng of these effects in the long term, without damaging the organism and without withdrawal symptoms. Although ginseng is not a panacea, it turns out that many common medicines outweigh not only the effect but even the price.

If you have really read the article here, you should be more receptive to the idea that despite the long list of ginseng effects, there is no placebo or " Wobenzym of the Middle Ages ", as a Czech chemist who has never read anything about ginseng. It can be more so that ginseng panaxosides are a model for the Parallel of the Future. The research of artificially modified panaxosides (see, for example, Kumar2009mmg ) is coming into fashion, which some company may soon be patented as its discovery and put it on the counter with the appropriate fanfare.