About the treatment of diseases
Simply put, health is the sum of many physiological parameters are kept in balance. A related term is homeostasis. In every environment on the body, factors that make it deviate from equilibrium. All of these factors is called stress in the broad sense, Czech just a burden. This burden organism in its adaptation range resists - adapts to it. If the load exceeds the adjustment range of the organism occurs term significant deviation from the physiological balance - illness or death.
Note: From the perspective of theoretical medicine , the definition of health oversimplified, but suffice here.
Paracelsian drugs - easy definition, difficult to use
According paracelsovského paradigm can be a cure any active substance, including poisons. Specifically, Paracelsian view between toxins and drugs not distinguish at all. If there is a specific indication (main effect), the therapeutic index of a substance (the ratio LD 50 / ED 50) is greater than 1, it may be considered Paracelsian cure. Historically himself Paracelsus used to treat mercury compounds, arsenic and other inorganic and organic toxins. On the easiest to understand that under the definition of modesty pay for drugs paracelsovských necessity
- precise, standardized to milligram dosage forms
- prudent prescribing and strict adherence benefits
For paracelsovských drugs not harmful unilateral action on physiological parameters. As a result, these can be used only when there is a deviation from the physiological balance - disease. When administered to a healthy individual Paracelsian drug causes a deviation in the opposite direction, opposite disease. Example: Atropine can be given as an antidote for the muscarinic poisoning. When administered to healthy subjects atropine alone poison. Another example: Insulin is the drug in diabetics with elevated blood sugar levels (hyperglycemia). If insulin administered to people with normal levels of sugar, leads to hypoglycemia, loss of consciousness and can be lethal.
Preferably paracelsovských drugs is that inexpensive definition gives us to choose from a large number of chemicals, among which are found effective antibiotics and other medications. The downside is the "side effects" (Paracelsian paradigm does not use the word virulence) that require precise dosage form and dosage. The doctor must "side effects" of drugs for the treatment paracelsovskými know and take into account.
Adaptogens - restrictive definition, easy to use
Unlike paracelsovských drugs is defined adaptogen more difficult. This restrictive definition, however, allows relatively easy usage and dosage. Adaptogens must not be one-sided effect on physiological parameters. Any deviation from normality can return adaptogen physiological parameter back towards health, but healthy may not cause a deviation opposite. Example: ginseng treated blood pressure reduction in some types of experimental hypertension ( Lee2016aek , Zhao2015epn , Lee2014rmp ). In patients with normal or reduced pressure, but does not cause hypotension ( Chen2012krg , Ping2011eas , Liang2005pns ).
Preferably adaptogens is that they can be used as if it were food. Specifically, in this category we have currently available for hundreds of medicinal plants whose consumption is for us due to our evolutionary past completely without danger. Disadvantage: Adaptogens are the definition of 'smart drugs' but today they largely rely on the internal intelligence of our body. Development of artificial adaptogens new generation will be because of this requirement significantly more difficult than the development of new drugs paracelsovských.