History adaptogens, Israel discovered Brechman, builds on theoretical medical term stress , whose exponent was János (Hans) Selye . Before I continue, let me ask - have you ever heard the term "theoretical medicine"? Because I've never met him nor in any medical book, nor later for the entire study physiology at the University. In doing so, theoretical biology is legitimate science that the UK lectures and theoretical physics is an everyday term ...
The theoretical versus practical science
Fortunately, it is not my task impromptu recite the definition of science, but common sense tells me that "most science" physics, biology and medicine until then. Furthermore, my intuition says that theoretical physics is the real physics, experimental physics while her maid (although reading). So it seems that the typical science, which is undoubtedly physics, the theory needs, even on the bases.
If we let talk common sense in biology, I hear that theoretical biology is exotic, but recognized discipline. It is as if the image of the absent-minded professor - on one side a bit "useless", on the other hand offers deep insights that would give us maybe once biologists and allow topping arrogant physicists, publishing in biological journals and losers for us having our own field. Biology would like based on their own theory beyond physical chemistry, but it's still - despite the heroic efforts of Wilson, Prigožinů and Žabotínských - in practice a few flourishes.
Entirely negative but the common opinion in medicine. I hear that the theoretical concept of medicine is puffy, exotic discipline, perhaps at best an introduction to medicine that each specific disease has a specific etiology and treatment of the true theory of molecular medicine is medicine that attracts lazy chatter and charlatans ... In addition to my intuition it seems that at one time - sometimes from 30th to 60th years of the 20th century - the theoretical medicine stared seriously, while today the theorists rather meet with indifference, which is a reflection of the declining interest in science in general, which is a reflection of ... but it would have got to the field of finance and it does not belong here. To find out what he thinks about theoretical medicine others, I punched after writing this paragraph, the word "theoretical medicine" into a search engine. Excerpts from the results:
- "For example, theoretical medicine while trying to figure out the causes of health and illness, practical medicine are simply trying to keep people healthy."
- Or: "Theoretical Medicine Biomedicine =" (read: theoretical medicine does not exist)
- Or "Originated theoretical medicine, maneuvered away from the life that many patients did not help." (from the history of medicine, here )
- One professor (Nicholas Popovich, b. 1941 Mukachevo) has a theoretical medicine among its specializations.
- Even in a pool of information reaches, called Wikipedia page "Theoretical Medicine" does not exist (even in English), once again we find only a handful of professors, vintage 40s.
The fate of a forgotten industry
So it seems that I was not so far from the truth. Medicine keeps saying she liked science, but when it comes to the crunch, so he holds the principle artisanship. The original idea of the founders of theoretical medicine, as was just Janosz / Hans Selye stress, or indeed even Israel Brechman with adaptogens , forgotten. Medical students with the theoretical concepts of medicine meet in introductory lectures, but theoretical medicine as a discipline, how I hear virtually ceased to exist. Stress and adaptogen colloquially in buzzwords and rushing to the theory experimenters do not have time. For example, Marina Davidovová in their review "Eleutherococcus senticosus as an adaptogen - a Closer Look" ( Siberian Ginseng as an adaptogen - a closer look) collected the detailed data about its phytochemistry, but theoretical medical meaning of the term adaptogen it already escapes. She had time to get acquainted with only a vulgarized version, which promptly dismissed. For stress can turn as exemplified essay Gerald Weissman "The experimental pathology of stress Hans Selye to Paris Hilton" (Experimental Pathology stress: From Hans Selye to Paris Hilton), where Weissman Selye mocks as forerunner "stressed" Paris Hilton, his theoretical work declares sebezviditelňování and practical experiments - which one can not deny the value - diminishes referring to previous authors. For Weissman but not the inability to understand something, but fun - Selye is just one of hundreds of victims of satire, an old man regularly entertains himself and his audience. In doing so, he inadvertently demonstrates how "normal" medicine theoretical medicine looks.
Einstein medicine is not welcome?
It was finally just Weissmanův article that brought me to the parallels between Selyem and Albert Einstein. Weissman eagerly betrays what is even respectable sources do not always we learn - namely that Selye prevented with the word stress for at least a year Walter B. Cannon ( Stresses and Strains of Homeostasis , 1935), while Selye's flagship publication "A syndrome produced by diverse nocuous agents " (syndrome caused by various harmful agents) appeared in Nature until a year later. It refers to earlier experiments dealing with corticosteroids in stress situations. That got me thinking. Even with Einstein could indicate a previously known Lorentz transformations - the discovery had "hung in the air." But he had come genius to it koheretně expressed as a coherent theory. Even Konrad Lorenz envious allege that the imprinting in goslings farmers say anything new, and Isaac Newton that apples fell long before the law of gravitation ...
Theorist blame of self-promotion
Selye in his lifetime he wrote more than 1,500 articles and research reports, roughly the same as his compatriot Pál Erdos, the most productive mathematician of all time. Why so many? It was only because sebezviditelňování as suspects Weissman? I think it was an attempt to grab elusive. He stood before a similar problem, as Doc. Anton Markos , who during his lecture Theoretical Biology kept repeating the same words and reading recommended texts with thousands of pages , although he actually tries the same - to generalize gene and breaking away from the slogan that "gene is a sequence of nucleotides in DNA."
Janosz / Hans Selye was productive experimentalist. In rats exposed to various stress factors proved except specific answers also nonspecific stress response (general adaptation syndrome - a term that has introduced himself Selye): enlargement of the adrenal glands, lymph nodes, thymus and reduction of hormonal changes. Compiled systematic classification of steroid hormones glucocorticoids (eg. Adrenal hormones), androgens and estrogens. He coined the term glucocorticoid and described the anti-inflammatory effects of corticosteroids for several years before this fact is clinically confirmed ( Szabo2012lhs ). But I made the greatest contribution Selyeho do not consider the introduction of new words, or research specific hormones, but that theory of stress and health, which Selye in their publications called unified theory of medicine and by general practitioners to this day more or less ignored.
Nobel Prize out of place
I do not know if the Nobel Prize - he said Feynman - second mistake of Alfred Nobel, but at least sometimes sitting there cowards. And I'm not talking not so much about ridiculous this year's Peace Prize to the European Commission (!), But also that the Nobel Committee did not dare to give the prize for Einstein's theory of relativity - got her "practical" photoelectric effect. Similarly Janosz / Hans Selye never had a chance to win a Nobel for a unified theory of medicine, as it was not possible to grant an ingenious Erdos for mathematics ... He had a chance to get it for glucocorticoids, which discovered and named. However, when in the 50s the price of glucocorticoids awarded, Selye was not on the list. Selye was later nominated for a Nobel 9 more times - each time unsuccessfully. Simply we live on a planet where the most prestigious scientific award for theoretical work does not.
Theoretical Medicine is now missing
The time has come to admit that I'm exaggerating a bit previous text. Theory of stress lives, mental stress was generalized as called. Allostatic load ( Mcewen2000aal ), examining the immune and neurological correlates of stress. Even theoretical medicine develops somewhere, even if only in a very narrow circle of candidates. Such as Bengt Brülde . Although Brülde their discipline called "practical philosophy" generally operates just hardcore theoretical medicine ( Brulde2001gmt , Brulde2000hdc etc.), personalized approach to medicine theory is Lewis S. Coleman , see his "30 years lost in anesthesia theory" (30 lost years theory anesthesia). Coleman after a long time opens Selye's theory of stress in surgical operations and attempts to abstract theory anesthesia procedure as mitigating the stress that would otherwise complex surgical operation entirely impossible. There are, of course, people who have physical superstring theory convicts ahead only because of cabalistic numbers degenerate dimension and they certainly condemn Coleman posts. Even abstract benefits but may ultimately lead to concrete changes, as well as a perpetual motion cheered progress in mechanics. I am glad to find doctors who the importance of theory in medicine and realize Selye's legacy approach with the seriousness it deserves.
The role of Prague in theoretical biology and medicine
Albert Einstein and Janosz / Hans Selye have shared even more thing: We both worked in Prague. Selye studied here (when it was Prague German University), while Albert Einstein here 100 years ago, discovered the general theory of relativity. Due to the Austro-Hungarian origin Janosz Selye's physiology in Prague is not surprising - the words biochemist and immunologist Felix Haurowitz, "All major German doctors worked at the medical faculty in Prague and in Würzburg." I wonder if Selye also stayed in Viničné 7, like Einstein, or down to Albert, welcome clarification.
Another anomaly Prague today's Department of Philosophy and History of Science Faculty of Science, which offers the field of theoretical and evolutionary biology, and which also operates a phenomenal Zdenek Kratochvil . In the words of Doc. Anton Markoš was the establishment of this department allowed the atmosphere early 90s of the 20th century and the vacuum after the abolition of the Institute of Marxism-Leninism. On the faculties of natural sciences ordinary university is supposed to set up this type of department or something unusual and exceptional.