In its area of origin, ginseng (whether asian or American ) is prescribed by the standard of sexual function. ( Murphy2002gsb ) While improving potency with ginseng is mostly easy to see, the greater the question of how much ginseng helps in its other traditional indication - to improve fertility.
What does science know about the effect of ginseng on fertility
A short answer to this question would be: relatively little. In comparison, for example, with cardiovascular effects, the traditional ginseng indication to increase fertility has been devoted to only ten publications. One of the first was the Italian Salvati1996epg clinical study, in which 30 male patients with reduced sperm count, and another group of 16 patients with idiopathic varicocele ginseng, significantly increased the number and activity of moving sperm. The chemoprotective effect of ginseng on the aspect of fertility was addressed in the Hwang2004pgi study, according to which the P. ginseng water extract protected guinea pigs from fertility impairment after exposure to polysorbed dibenzodioxin. An experiment with the same dioxin and similar results was repeated in rats ( Park2006tet ). Later, the protective effect of red ginseng extract from the reproductive toxicity of ethanol ( Jang2011erg ) was examined with positive results. The radioprotective effect of c-ray radiation on testicular tissue was reported in mice ( Kumar2003rep ). Another experimental study ( Sawiress2011ege ) also claims that ginseng improved fertility in diabetic rats. The disadvantage of this last study is, in my opinion, the low number of experimental animals (10 treated, 10 positive controls, 10 negative controls, together 30 rats), which a priori does not allow for highly significant conclusions. Perhaps most convincing is the latest Italian clinical trial, Cai2012sqp , where 206 patients with genital chlamydia ( Chlamydia trachomatis ) were observed, with the conclusion that ginseng use together with antibiotics against chlamydiosis resulted in a relative improvement in the quality of the seed.
Effect of panaxosides on sperm capacity
Sperm capability is a process in which sperm after ejaculation gain the ability to fertilize an egg. The influence on capacity has been investigated for typical ginseng content - panaxosides. It is not clear whether this effect is associated with the aforementioned improvement in fertility or that it is an independent effect. Researchers on capacity considerations may have brought about the recently explained role of ginseng in the NO cascade , which is also responsible for erection . In particular, ginsenoside Re was found in vitro to improve mobility ( Zhang2006gif ) and human sperm ( Zhang2006gif ) capacity. Ginseng also contributes to fertility by increasing libido and increasing the volume of ejaculate that is important for successful fertilization. The NO cascade plays a role not only in male erection, but also in female orgasm, which is very important for fertilization.