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Autoimmune diseases

Immunity and brain are the two most complex body systems. Their diseases are also quite complex. Brain in mental illness works almost correctly, only bad conclusions are made. Similarly, the immune system in autoimmune disease works almost correctly, but attacks its own antigens . Therefore, on our own cells and proteins. The medical science of repair of these complex systems does not hold. It solves the situation by simply shutting it down. For psychiatric illnesses, psychiatrists disrupt the entire dopaminergic path, thus preventing the patient's frontal lobe to invent crazy plans. It's called pharmacological lobotomy. Similarly, in autoimmunity physicians disable the immune system by immunosuppressive therapy. Autoimmune diseases are large numbers and have different names depending on which tissues affect:

But standard treatment is always one: disabling the immune system by corticosteroids (prendison) or other immunosuppressants (azathioprine, etc.). Untreated autoimmunity leads to chronic inflammation and premature aging of the affected tissue. In the worst case, the irreversible destruction of the affected cell population - such as brain cells. But regenerating can not even pancreatic β-cells, the destruction of which is the essence of type 1 diabetes ...

Undesirable effects of immunosuppressive

Administration of immunosuppressants leads to a loss of resistance to common microbes, which is resolved by the administration of antibiotics , thus developing particularly resistant so-called hospital MDR strains of microbes. However, corticoids are much more harmful - see Buchman2001sec . These are analogues of stress hormones (aldosterone, cortisol ...) so that their administration keeps the body in constant hormonal stress . Therefore, the immune response is turned off, which, due to the high level of stress indicators, is postponed to later periods of stress. But the extreme hormonal stress that the body can withstand without harm for only a few days lasts forever. Administration of corticosteroids thus leads to catabolic changes, osteoporosis, atrophy of the muscles and atrophy of the adrenal gland, which are unnecessary. And last but not least, to hunger, overeating, obesity and hyperlipidemia. And there are even worse immunosuppressants such as cytotoxic methotrexate that directly kills leukocytes and other active cells. The question is: Is it possible to substitute or reduce dosing of standard immunosuppressants by properly selected phytotherapy?

TČM and Ajurvéda have something to say about treating autoimmune diseases. Indeed, even in our medicine, immunosuppressants are rich in natural origin. Traditional systems also use poisonous herbs such as Carmichael's ( akonitin ) and Wilford's triplets (triptolide), similar to autoimmunity. For those who do not know, the non-scientific TČM is a medicine with everything and works with the sharpest poisons that the doctor carefully cares for the dosage. But we will be especially interested in adaptogens that can be given to the patient without fear.

Managing the autoimmunity of adaptogens

Classical adaptogens often have anti-inflammatory and regenerative effects to alleviate both autoimmune and standard treatment:

  • Vitaminic snoring (so-called Indian ginseng) is an adaptogen with anti-inflammatory to moderate immunosuppressive effects. The used part is the root in which vitaferins, vitanolides and other saponins accumulate, the most effective of which is vitaferin A. The dried root of vitania is nicknamed "Indian ginseng", but the effect profile is not identical with the ginseng. There is experimental evidence that vitania can be effective against rheumatic arthritis ( Khan2015ews ) and lupus ( Minhas2012tew ).
  • Gennady's true vitamin resembles anti-inflammatory effects , but is less immunosuppressive and more regenerative. Several papers show the efficacy of ginseng right in atopic dermatitis ( Lee2011ekr , Kim2011eta , Sohn2011ekr , Lee2011krg , Cho2013ekr ). In rheumatoid arthritis, ginseng suppresses inflammation by reducing the STAT3 transcription factor phosphorylation and decreasing Th17 cell counts ( Jhun2014rge ). The Etemadifar2013gtf study demonstrates the effect of ginseng against fatigue in multiple sclerosis, the Yang1986sl study mentions the efficacy of panaxoside against lupus. Ginger lectins in the mouse model restricted autoimmune brain damage ( Hwang2011app ). Due to the large number of work on this plant, the references I have submitted are incomplete. In case of interest I recommend a separate search, you can start with the effects of ginseng against inflammation and fatigue .
  • Glossy gloss protects cells against autoimmunity by activating FOXP3 + T reg lymphocytes ( Ma2015aeg ).

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