Diabetes mellitus (diabetes) is a generic name for a group of chronic diseases whose common symptom is elevated blood glucose. There are two basic types: type I diabetes and diabetes II. Type I diabetes is autoimmune (cells of the pancreas that produce the insulin hormone are destroyed). Type II diabetes. is caused by decreased tissue sensitivity to insulin.
Diabetology is the whole medical branch. Diabetes is related to virtually all physiological systems, fat metabolism, obesity , cardiovascular system , immunity ... It is therefore not possible to describe diabetes and its complications briefly. The goal of diabetes treatment is to maintain normal blood glucose levels and to treat causes (for example autoimmune).
Methods of treatment of elevated blood sugar
Depending on how they achieve blood sugar reduction, the drugs can be divided into several types ( Elabhar2014pdr ). Specifically, these are the following mechanisms of action:
- increased insulin level or efficiency
- reducing the absorption of sugar from the digestive system
- increased use of glucose in tissues (head in fat and muscle)
- reducing blood glucose levels by affecting the activity of the liver
- activation of nuclear PPAR receptors
- increasing the level or effectiveness of adiponectin
- other pathways (incretin, endogenous opioids)
- antioxidant effect
I consider the antidiabetic effects of herbs as a particularly interesting effect on PPAR receptors and other hormonal pathways (incretin, opioids). PPAR agonists are commonly prescribed for diabetes.
Pragmatically, it is a diabetes epidemic that has not been tackled by the 20th century medicine. There are currently approximately 150 million diabetics in the world, and this figure will double in 2025. It is also pragmatic that there are medicinal plants that have been found to be more or less clinically proven to be antidiabetic, and that doctors know relatively little about these herbs. Diabetes can not be healed yet - once we get diabetes, it just goes on. However, healing herbs should not be underestimated as a means of preventing, slowing down diabetes, and alleviating its symptoms and consequences.
Ginseng adjusts glucose and cholesterol levels
Ginseng right is one of the main antidiabetic herbs TČM ( Lim2009egv ). There are 300+ scientific publications on its effect on diabetes. It helps regulate blood glucose at multiple levels, influenced by PPAR receptors ( Chung2001cbw , Yoon2003ppr ), which act on ginsenosides Rg 3 ( Hwang2009aeg ), Rh 1 ( Gu2013gra ) and Rb1 ( Chan2012gpa ). In addition to lowering blood sugar levels, ginseng also regulates cholesterol, whose increased levels of diabetes often accompany ( Ni2010sgp and others). Ginseng manages diabetes by modifying gene expression ( Banz2007gmd ), has a hypoglycaemic effect ( Jeon2013aef ) and protects against diabetic atherosclerosis ( Zhang2006msc ). Ginsenoside Re increases tissue sensitivity to insulin ( Gao2013grr ). American ginseng and notoginseng ginseng are considered less encouraging, but anti-diabetes acts just like ginseng right.
A common complication of diabetes is ischemia of the limbs (eg venous ulcers). These ginseng heals both by improving blood circulation and by its healing effect ( Chen2008cpe ). Ginseng has a dual, opposed effect on capillary growth: ginsenosides Rg1 and Rg3 act by activation ( Kwok2012sg2 ), Rb1 inhibitory ( Sengupta2004may ). Many other publications document the protective effect of ginseng against organ damage (brain, heart, liver, kidney, retina) due to diabetes and protective and healing effects in heart and stroke . Otherwise, ginseng is harmless and safe .
Other adaptogens with antidiabetic effect
Diabetes completely destroys health and thus offers adapters a lot of opportunities to apply their healing effects. Medicinal plants helping to prevent and treat diabetes are therefore large. Their effects complement each other and intensify, so combinations of antidiabetic adaptogens usually lead to better results. From literary sources ( Elabhar2014pdr and others) I offer a selection of antidiabetic adaptogens and medicinal herbs:
- Often, diabetes is used in the treatment of diabetes in combination with Chinese koptis ( Liu2013aet , Zhen2011aec ). Shishak does not have the direct glucosine effect of ginseng ( Xie2009aea ). Its flavonoids slow down glucose absorption by blocking intestinal α-glucosidase ( Yang2015dai ), help with its strong antioxidant effects ( Shang2010gse , Waisundara2008sbe ) and protect against complications of diabetes ( Xiao2014pte ). Vogonin acts on PPAR? Receptors in fat cells (important in diabetes) and changes their gene expression ( Zhang2015wso ). Bajkalin and vogonin protect the brain ( Ma2015bad ) and the heart from diabetic damage ( Khan2016wad ). In animals, shihak improved erection disrupted by experimental diabetes ( Li2016bes ). Strawberry extract in experimental diabetic mice improves impaired fat metabolism and normalizes body weight ( Song2013esb ). Flavonoid vogonin works against heart damage due to diabetes ( Khan2016wad ).
- Ginseng is combined in the treatment of diabetes according to TCM with a multivalent rhythm that improves fatty metabolism in diabetes ( Kho2016cwr ).
- The antidiabetic herbs according to TČM are also sticky remormes, Thunberg 's pear, the fragrant crown and the so-called hatka kumbu ( Elabhar2014pdr ).
- Grazing hay is a traditional remedy against civilization diseases and diabetes. Its effect is documented by eg Gaddam2015rfp .
- Tapestry's Fountain is the traditional anti-diabetes remedy in Mexico.
- Musketeer and other types of Abelmoschus are traditional in diabetes in India, as well as the lover , the creeper and the Indian zederach .
- Ayurvedic commonwealth and other Salacia species ( S. reticulata , S. prinoides , S. chinensis ) treat diabetes and act against obesity, inter alia, by acting on PPAR receptors.
- Puck's gorgeous is traditional anti-diabetes and obesity in the Far East. It contains, for example, triterpenoid acid corozol.
- Cecrocopy tupolist , a traditional medicinal plant of Central America, has a strong hypoglycemic effect. This plant also acts against asthma and has a relaxing effect on the blood vessels. All these features make it interesting for diabetes treatment.
- Momordika bitter contains an analogue of insulin and other substances against obesity and diabetes.
- Karaluma Sinai is traditional anti-diabetes in the Middle East ( Habibuddin2008aea ).
- Common food ingredients garlic kitchen , raw onion kitchen and chilli peppers help against diabetes. Do not underestimate.
- Basil Sacred is a traditional Indian adaptogen with anti-diabetes ( Suanarunsawat2016aaa ) and lipid imbalance accompanying diabetes ( Husain2015aeo ).
- Anti-diabetic effect also has Ayurvedic asparagus and asparagus ascending . Helps our asparagus ( Hafizur2012aoe ).
- Stévie sweet is not only a non-calorie sweetener, but also an antidiabetic plant ( Ritu2016ncs ).
- The effects on PPAR receptors and other mechanisms in diabetes also benefit from rosemary , sage , horseradish , redcurrant , marjoram , corn juniper , nettle nettle , green tea and Pickering's clementine .
- In diabetes, the complication of which is cirrhosis, is advantageously used by the mammoth thistle .
To assemble the right antidiabetic combination for a particular patient may not be easy, but from what do we have the diabetologists and practitioners of the TCM ... Like the prevention of atherosclerosis , the prevention and treatment of diabetes is a matter of lifelong eating. You can recommend a varied menu where "varied" means it will contain a number of different antidiabetic adaptogens, with emphasis on those that are easily available in us - onions, garlic, oregano, rosemary, nettle, green tea, asparagus and common types of healthy vegetables, which I omitted from the enumeration of antidiabetic plants.
Glossy Glossy has extensive effects on diabetes
Triterpenoids of polysorbates release insulin and reduce glucose by treatment with tyrosine phosphatase 1B, aldose reductase, α-glucosidase and other enzymes. Lesklokorka is an exceptional immunomodulatory adaptogen and in this way treats diabetes ( Ma2015aeg ), which is closely related to disorders of the immune system.
Study on experimental diabetes induced by artificial destruction of Langerhans islets: In mice ( Li2011aeg ), proteoglycans of G. lucidum were already at a low dose (50 mg / kg) even more markedly at a high (150 mg / kg) normalized blood sugar level. The effect of glans was practically the same as positive control (glibenclamide). Interestingly, glycocortico proteoglycans have also normalized lipid metabolism, which has led to conclusions about the potential of glans in atherosclerosis. The same results were found in further work in mice ( Wang2012enp ) and rats ( Zheng2012glp ). Experimentally, the positive effect was also found in complications of diabetes ( wound healing , mouse, Tie2012glp ). Regarding the mechanism of action, Teng2012 claims that gloss has an effect on phosphorylation of the insulin receptor. The work of Fatmawati2011srg further measured that ganoderic acid C2 inhibits aldose reductase and thus protects against complications of diabetes. In addition, proteoglycans have a glossy effect on pancreas inflammation that leads to diabetes ( Li2016tkg ). These and other anti-diabetic effects of glossy bronchus summarize the Ma2015aeg review .
Other antidiabetic sponges
In addition to the nonspecific medicinal effects given by their ergosterol and β-glucan content, edible and adaptive fungi have specific anti-diabetic effects:
- Chinese caterpillar is an immunomodulatory adaptogen. It protects pancreatic β-cells ( Liu2016hmc ) and belongs to potentially effective anti-diabetic fungi ( Paterson2008ctc ).
- The antidiabetic effects of oyster mushroom are documented in 20+ experimental studies. According to the Jayasuriya2015hac clinical study, people with type 2 diabetes at a dose of only 50mg / kg reduced glucose and increased insulin levels. Similar results were seen in rats at doses of 250-1250 mg / kg ( Jayasuriya2012 ). In addition, the clover contains lovastatin blocking cholesterol synthesis.
Although mushrooms are less well researched, it is clear from the above that fungal nutrition should be an integral part of the diet of diabetics and people with a family history of diabetes .
Fruit diet of diabetics
Additionally, many types of fruit can be included in the antidiabetic adaptogens, especially the so-called superovulation. But beware of sugary garden fruits (apples, pears, plums, strawberries, etc.)! Treatments for diabetes are better suited for small and wild fruit adaptogens:
- blackberries ( Rubus fruticosus )
- black currant ( Ribes nigrum )
- medical bear
- the sculptor
- downy corn ( Cornus mas and Cornus officinalis )
- bumblebee ( Prunus laurocerassus )
- shrubs and other types of berries ( Sorbus )
- sea buckthorn
- hawthorn ( Crataegus )
- cherry ( Prunus cerasus )
- Sorbus domestica
- Mespilus germanica
- aronia ( Aronia melanocarpa )
- ovalový okázalý
- wild tomatoes
- aubergine black
- + many other species of wild and grown supercoiled
For diabetics, eating wild berries is a particularly cruelty because fluctuating levels of glucose and insulin make them particularly tedious after hunger. The wild supercoat is acidic and bitter because it contains especially many acidic vitamins, flavonoids and other miraculous substances, such as ursolic acid and corozol. I personally would be frustrated with the diabetes by combining blueberries, dandelions, arrows, medallions and a varied selection of fruit from the miraculous family of aubergine. For interest only, "Indian ginseng" is a sweet-smelling vitamin , which I recommend to grow. Roots are routinely used, but its fruits resemble mochin and the bruising of diabetics - as well as the fruits of the mochin - are superbly suited.
Technique of diabetes management
For most diabetics, it is necessary to install a steel lock with a lock on the fridge at home. The door to the pantry room must be locked. No sugar, honey, bread, pastry or cereals, biscuits and sweets should be stored in the kitchen. Because of the wildly fluctuating levels of insulin, which is also a hormone of hunger, the hypothalamus of diabetics lives in a state of chronic horror death starvation. As a result, most diabetics (many of whom have been obese before the outbreak) have an unmet need to eat and have no ability to follow prescribed diets. Keys from the fridge and pans and the preparation of food must be in the hands of a responsible commissioner, who also monitors the weight and blood pressure of his trustee daily. In addition to the knowledge of diabetic cooking, the prominent guardian also has a sadistic talent to resist the excitement and threats of a desperate diabetic who wants to jump between meals. In diabetic patients with hysterical inclinations, it is sometimes impossible for a family member to be a prominent guardian and must be an unrelated physician, nurse or hired caretaker, before whom the diabetic is ashamed to shed their scenes. Diabetes should have no "candy against hypoglycemia", it must be in the hands of the said guardian. In order to get rid of the worst hunger, a proficient guardian between meals can give the diabetic, for example, an emergency portion of sweet vegetables (carrot, tomato, pepper) combined with healthy fats (rapeseed oil, olive oil, soybean, sesame oil, (sunflower, pumpkin seed, poppy, sesame, flax, peanuts, almonds, almonds, walnuts, hazelnuts, pistachios, etc.). Be sure to avoid the hazelnuts, their bacon, grains, cereals (roasted corn, the oil is too saturated. In the event that a diabetic on a proviant guardian attacks the weapon in his hand, a soybean can be worn in his pocket.