Diabetes mellitus (diabetes) is a generic name for a group of chronic diseases whose common symptom is elevated blood glucose. There are two basic types: type I diabetes and diabetes II. Type I diabetes is autoimmune (cells of the pancreas that produce insulin hormone are destroyed). Type II diabetes. Is caused by decreased tissue sensitivity to insulin.
Diabetology is the entire medical branch. Diabetes is related to virtually all physiological systems, fat metabolism, obesity , cardiovascular system , immunity ... It is therefore not possible to describe diabetes and its complications briefly. The goal of diabetes treatment is to maintain normal blood glucose levels and to treat causes (for example, autoimmune).
Methods of treatment of elevated blood sugar
Depending on how they achieve blood sugar reduction, the medication can be divided into several types ( Elabhar2014pdr ). Specifically, these are the following mechanisms of action:
- Increase in insulin level or efficiency
- Reducing the absorption of sugar from the digestive system
- Increased use of glucose in tissues (head in fat and muscle)
- Reducing blood glucose levels by affecting the activity of the liver
- Activation of nuclear PPAR receptors
- Increasing the level or efficacy of adiponectin
- Other pathways (incretin, endogenous opioids)
- Antioxidant effect
I consider the antidiabetic effects of herbs as a particularly interesting effect on PPAR receptors and other hormonal pathways (incretin, opioids). PPAR agonists are commonly prescribed for diabetes.
Pragmatically is the diabetes epidemic, with which the medicine of the 20th century has not been counted. There are currently approximately 150 million diabetics in the world, and this figure will double in 2025. It is also pragmatic that there are medicinal plants that have been found to be more or less clinically proven to be antidiabetic, and that doctors have relatively little knowledge about these herbs. Diabetes can not be treated yet - once we get diabetes, it only progresses. However, medicinal herbs should not be underestimated as a means of preventing, slowing down diabetes, and alleviating its symptoms and consequences.
Ginseng adjusts glucose and cholesterol levels
Ginseng right is one of the main antidiabetic herbs TČM ( Lim2009egv ). There are 300+ scientific publications on its effect on diabetes. It helps regulate blood glucose on multiple levels, influenced by PPAR receptors ( Chung2001cbw , Yoon2003ppr ), which act on ginsenosides Rg 3 ( Hwang2009aeg ), Rh 1 ( Gu2013gra ) and Rb1 ( Chan2012gpa ). In addition to lowering blood sugar levels, ginseng also regulates cholesterol, whose increased levels of diabetes often accompany ( Ni2010sgp and others). Ginseng modifies diabetes by modifying gene expression ( Banz2007gmd ), has a hypoglycaemic effect ( Jeon2013aef ) and protects against diabetic atherosclerosis ( Zhang2006msc ). Ginsenoside Re increases tissue sensitivity to insulin ( Gao2013grr ). American ginseng and notoginseng ginseng are considered less encouraging, but anti-diabetes acts just like ginseng right.
A common complication of diabetes is ischemia of the limbs (eg venous ulcers). These ginseng heals both by improving blood circulation and by its healing effect ( Chen2008cpe ). Ginseng has a dual, opposed effect on capillary growth: ginsenosides Rg1 and Rg3 act by activation ( Kwok2012sg2 ), Rb1 inhibitory ( Sengupta2004may ). Many other publications document the protective effect of ginseng against organ damage (brain, heart, liver, kidney, retina) due to diabetes and a protective and healing effect in heart and stroke . Otherwise, ginseng is harmless and safe .
Other adaptogens with antidiabetic effect
Diabetes completely destroys health and offers many opportunities for adaptogens to exert their curative effects. Medicinal plants helping to prevent and treat diabetes are therefore large. Their effects complement each other and generally intensify, so combinations of antidiabetic adaptogens usually result in better results. From literary sources ( Elabhar2014pdr and others) I offer a selection of antidiabetic adaptogens and medicinal herbs:
- Often, diabetes is used in the treatment of diabetes in combination with Chinese koptis ( Liu2013aet , Zhen2011aec ). Shishak does not have the direct glucosine effect of ginseng ( Xie2009aea ). Its flavonoids slow glucose absorption by blocking intestinal α-glucosidase ( Yang2015dai ), helping with its strong antioxidant effects ( Shang2010gse , Waisundara2008sbe ) and protecting against complications of diabetes ( Xiao2014pte ). Vogonin acts on PPAR? Receptors in fat cells (important in diabetes) and changes their gene expression ( Zhang2015wso ). Bajkalin and vogonin protect the brain ( Ma2015bad ) and the heart from diabetic damage ( Khan2016wad ). In animals, shihash improved erection disrupted by experimental diabetes ( Li2016bes ). Strawberry extract in experimental diabetic mice improves impaired fat metabolism and normalizes body weight ( Song2013esb ). Fogonoid vogonin works against heart damage due to diabetes ( Khan2016wad ).
- Ginseng is combined in the treatment of diabetes according to TCM with a multivalent rhythm that improves fatty metabolism in diabetes ( Kho2016cwr ).
- The antidiabetic herbs according to TČM are also sticky remormes, Thunberg 's pear, the fragrant crown and the so-called " hull" ( Elabhar2014pdr ).
- Greek hay fever is a traditional remedy against civilization diseases and diabetes. Its effect is documented by eg Gaddam2015rfp .
- Tapestry's tapestry is the traditional anti-diabetes remedy in Mexico.
- Musketeer and other types of Abelmoschus are traditional in diabetes in India, as well as lobster , cobweb and Indian zederach .
- Ayurvedic Commonwealth and other Salaces ( S. reticulata , S. prinoides , S. chinensis ) treat diabetes and act against obesity, inter alia, by acting on PPAR receptors.
- Puck's magnificent is traditional anti-diabetes and obesity in the Far East. It contains, for example, triterpenoid acid corozol.
- Cecropia tupolista , a traditional medicinal plant of Central America, has a strong hypoglycaemic effect. This plant also acts against asthma and has a relaxing effect on the blood vessels. All these features make it interesting for diabetes treatment.
- Momordika bitter contains insulin analog and other anti-obesity and diabetes substances.
- Karaluma Sinai is traditional anti-diabetes in the Middle East ( Habibuddin2008aea ).
- Common food ingredients garlic kitchen , raw onion kitchen and chilli peppers help against diabetes. Do not underestimate.
- Basil Sacred is a traditional Indian adaptogen with effects against diabetes ( Suanarunsawat2016aaa ) and lipid imbalance accompanying diabetes ( Husain2015aeo ).
- The antidiabetic effect also has Ayurvedic asparagus and asparagus ascending . Helps our asparagus ( Hafizur2012aoe ).
- Stévie sweet is not only a non-calorie sweetener, but also an antidiabetic plant ( Ritu2016ncs ).
- The effect on PPAR receptors and other mechanisms in diabetes also benefit from rosemary , sage , horseradish , currant , garden marjoram , corn juniper , nettle nettle , green tea and Pickering clementine .
- In diabetes, the complication of which is cirrhosis is advantageously used by the mammoth thistle .
To assemble the right antidiabetic combination for a particular patient may not be easy, but from where do we have diabetologists and TCM practitioners ... Like the prevention of atherosclerosis , the prevention and treatment of diabetes is a lifetime issue. You can recommend a varied menu where "varied" means that it will contain a number of different antidiabetic adapters, with emphasis on those that are readily available in our country - onion, garlic, oregano, rosemary, nettle, green tea, asparagus and common vegetables, Which I omitted from the enumeration of antidiabetic plants for brevity.
Glossy Glossy has extensive effects on diabetes
Triterpenoids of polysorbates release insulin and reduce glucose by treatment with tyrosine phosphatase 1B, aldose reductase, α-glucosidase and other enzymes. Lesklokorka is an exceptional immunomodulatory adaptogen and in this way treats diabetes ( Ma2015aeg ), which is closely related to disorders of the immune system.
Study on experimental diabetes induced by artificial destruction of Langerhans islets: In mice ( Li2011aeg ), G. lucidum proteoglycans already at a low dose (50 mg / kg), even more strongly at a high (150 mg / kg) normalized blood sugar level. The effect of glans was practically the same as positive control (glibenclamide). Interestingly, glycocortico proteoglycans have also normalized lipid metabolism, which has led to conclusions on the potential of glans for atherosclerosis. The same results were also found in other work in mice ( Wang2012enp ) and rats ( Zheng2012glp ). Experimentally, the positive effect was also found in complications of diabetes ( wound healing , mouse, Tie2012glp ). Regarding the mechanism of action, Teng2012 claims that gloss has an effect on phosphorylation of the insulin receptor. The Fatmawati2011srg study further found that ganoderic acid C2 inhibits aldose reductase and thereby protects against complications of diabetes. In addition, proteoglycans have a glossy effect on pancreas inflammation that leads to diabetes ( Li2016tkg ). These and other anti-diabetic effects of glossy bronchus summarize the Ma2015aeg overview.
Other antidiabetic sponges
In addition to the nonspecific therapeutic effects given by their ergosterol and β-glucan content, edible and adaptive fungi have specific anti-diabetic effects:
- Chinese caterpillar is an immunomodulatory adaptogen. It protects pancreatic β-cells ( Liu2016hmc ) and belongs to potentially effective anti-diabetic fungi ( Paterson2008ctc ).
- The antidiabetic effects of oyster mushroom are documented by 20+ experimental studies. According to the Jayasuriya2015hac clinical study, people with type 2 diabetes at a dose of only 50mg / kg reduced glucose and increased insulin levels. Similar results were seen in rats at doses of 250-1250 mg / kg ( Jayasuriya2012ha ). In addition, the clover contains lovastatin blocking cholesterol synthesis.
Although mushrooms are less well researched, it is clear from the above that fungal nutrition should be an integral part of the diet of diabetics and people with a family history of diabetes .
Fruit nutrition of diabetics
Additionally, many types of fruit can be included in the antidiabetic adaptogens, mainly so called superovascular. But beware of sugary garden fruits (apples, pears, plums, strawberries, etc.)! Treatments for diabetes are best suited to adaptogens from the ranges of small and wild fruits (so-called superovasculars):
- Blackberries ( Rubus fruticosus )
- Black currant ( Ribes nigrum )
- Medical bear
- The sculptor
- ( Cornus mas and Cornus officinalis )
- Bumblebee ( Prunus laurocerassus )
- Shrubs and other berries ( Sorbus )
- Sea buckthorn
- Hawthorn ( Crataegus )
- Cherry ( Prunus cerasus )
- Sorbus domestica
- Mespilus germanica
- Aronia ( Aronia melanocarpa )
- Ovalový okázalý
- Wild tomatoes
- Aubergine black
- + Lots of other species of wild and grown supercoiled
For diabetics, consumption of wild fruits is a particularly cruelty, because fluctuating levels of glucose and insulin cause them a particularly tedious hunger for sweetness. The wild supercoat is acidic and bitter because it contains especially many acidic vitamins, flavonoids and other miraculous substances, such as ursolic acid and corozol. I personally would be frustrated with the diabetes by combining blueberries, dandelions, arrows, medallions, and a varied selection of fruits from the miraculous family of aubergine. For interest only, "Indian Ginseng" is a sweet-breasted honey , which I recommend to grow. Roots are routinely used, but its fruits are reminiscent of mochin and the abuse of diabetics - as well as the fruits of the mochin - are suited.
Technique of diabetes management
For most diabetics, it is necessary to install a steel lock with a lock on the fridge at home. The door to the pantry room must be locked. No sugar, honey, bread, pastries or cereals, biscuits and sweets should be stored in the kitchen. Due to the wildly fluctuating level of insulin, which is also a hormone of hunger, the hypothalamus of diabetics lives in a state of chronic horror starvation. As a result, most diabetics (many of whom were obese before the outbreak) have an unmet need to eat and have no ability to follow the prescribed diet. Keys from the fridge and pans and food preparation must be in the hands of a responsible commissioner, who also daily monitors the weight and blood pressure of his fetus. In addition to knowledge of diabetic cooking, the prominent guardian also has a sadistic talent to resist the excitement and threats of a desperate diabetic who wants to jump between meals. In diabetic patients with hysterical inclinations, it is sometimes impossible for a family member to be a prominent guardian and must be an unrelated physician, nurse or hired caretaker, before whom diabetics are ashamed to venture their scenes. Diabetes should not have any "candy against hypoglycemia", it must be in the hands of the said guardian. In order to overcome the worst hunger, a proficient guardian between meals can give the diabetic, for example, an emergency portion of sweet vegetables (carrot, tomato, pepper) combined with healthy fats (rapeseed oil, olive oil, soybean, sesame oil, Pasta, cereals (roasted corn, oat flakes ...) and dry fruits (sunflower, pumpkin seed, poppy seeds, sesame seeds, peanuts, almonds, almonds, walnuts, pistachio etc.) The oil is too saturated. In the event that a diabetic on a prolific guard intervenes with a gun in his hand, a soybean can be worn in his pocket.