If herbal remedy has a weakness, it is precisely in the field of antibiotic effects . This is because there is a constant evolutionary chemical struggle between herbs and bacteria, in which bacteria, thanks to their short generation time, are clearly on the top. Infectious disease developers, responsible for the high mortality of infants, children and adults, who used to be the rule in the past, have long developed resistance to common and less common antibiotic herbs that were commonly used in the past. One reason why herbal medicine in the 20th century was worth surviving was the triumph of penicillin and other new antibiotics over traditionally used herbs. The reason was that the newly introduced antibiotics were not known in the world of bacteria. It is no longer the case today. Strains of antibiotic resistant strains (MRSA strains) are common today, and there is a need for antibiotics that are even newer and more irresistible - we are involved in a chemical weapons plant with organisms whose typical generation time is 30 minutes. Compared to infectious diseases , non-infectious diseases are evolving and traditional herbs are treated as hard as they once were. But back to the antibiotics.
Types of antibiotics
Depending on the type of germs germans, antibiotics are divided into:
- bactericides and bacteriostatic - antibacterial
- antimycotics and mycostatics - destroys fungal pathogens
- antiprotozoal drugs - destroys protozoans
- antihelmintics and other antiparasitics - against worms and other internal parasites
Antibiotics in the narrow sense include only antibacterial agents, sometimes also antibiotic antiprotozoar. Thus, doctors may recommend patients with mycosis to avoid using antibiotics in the narrower sense that often promotes fungal infections. Anti-virus drugs (antiviral agents) do not count among antibiotics. Thus, doctors can give patients an important recommendation not to take antibiotic viral diseases.
Antibiotic counter antiseptic
The key feature of antibiotics is their therapeutic index - the ratio of effective and toxic dose. In other words, antibiotics must be much more toxic to pathogens than to humans. This is an important limitation that excludes many antimicrobial-active substances from the category of curable antibiotics that can be used as a mere antiseptic - ie, for external disinfection and surface cleaning. For example, alcohol (70% ethanol) is an excellent harmless antiseptic for disinfecting skin and surfaces (not plexi!), Which also destroys viruses. However, alcohol is totally unusable to fight internal infections because it is as toxic to humans as it is for microbes. In addition, good antibiotics may not decompose in the stomach and must pass into the bloodstream and target tissues. The development of new good antibiotics, or their bioprospecting in previously unexplored species of living organisms, is therefore difficult. Good antibiotics must be weighed and used only in patients who really need them to prevent the spread of resistant strains of pathogens.
Just because they are so rare, antibiotics take a lot of baffles and relatively toxic substances only when they heal the resistant infection they are struggling with. Since Paracelsus has been used to treat syphilis and other infections in Europe, violent poisonous mercury has been used. (The pearl is that Paracelsa accused the Gray of a Dutch importer of competing guajak wood, which was, of course, against syphilide ineffective, and another parachute is that Paracelsus probably died of chronic mercury poisoning, see Paracelsus medications .) Mercury on Paracelsus antibiotics list at 20. století doplnil arsen, vizmut a jejich sloučeniny.There have been attempts to internally use antiseptic colloidal silver. Paracelsus's drug therapy eventually (temporarily) triumphed over the infections first with sulfonamides and later with beta-lactam antibiotics (penicillin, cephalosporin, ...) whose therapeutic index was already relatively good. The series of paracelsal antibiotics supplemented with tetracycline and other effective antibacterial poisons. As Paracelsus drugs, the famous 20th century antibiotics need precise dosing, so it is necessary to prepare them in exactly standardized dosage forms (tablets, drops, injections ...). These forms of medicine have become a symbol of advances in drug therapy and the superiority of industrial drugs over previously used drugs in natural form.
A little theoretical medicine ...
It could be continued, for example, that, against diseases that do not receive resistance (such as atherosclerosis , diabetes and other civilization diseases), traditional herbs still occupy today as well as they once did. Or the fact that cancer is at the border between infections and civilization diseases because it evolves but only within an individual patient. Cancer is not portable (except for the cancer of the bear's devil's liver, which is transmitted to other devils by a bite) and the resulting evolutionary experience does not pass on to future generations. Therefore, anti-rabies are still as well (or poorly) as they once were. Or the way European surgeons enjoyed when Joseph Listerdiscovered and introduced aseptic surgery (using antiseptic carbone, as the phenol once used to be), so that patients stopped dying of infection and European surgeons could discover more and more complex life-saving rescue operations. Or, with our generation age of 20 to 30 years, we have not the slightest chance to compete with microbes in evolutionary terms, so that, in fact, microbes and viruses of most illnesses take us grace to kill us immediately and instead to make us bacillo. Their hosts quickly kill only evolutionarily young, inexperienced diseases such as swelling plague or ebola. Syphilis also shows a gradual decrease in virulence that occurred in Europe over the centuries of history of this disease. Or where our immunity goes,when today our newborns do not have to demonstrate their fitness to survive childhood infections and their mothers ability to protect their immunoglobulins in breast milk. Sooner or later, we either have to return to a more natural way of life and a more natural ratio of child mortality, or the evolution of our immunity will have to be taken artificially by gentlemen with white cloaks and good intentions. But I do not want to talk about it. That would be too much for the very important issues herewho are herewho are heresomewhat unsuccessfully trying to avoid ...
Antibiotic effects of natural medicines
All organisms face a continuous onslaught of microbes from the environment. It is therefore not surprising that plants, fungi and animals contain poisons called antibiotics. An exception is not a human being: We release β-defensins on the surface of the skin and mucous membranes, which are our natural antibiotics that are effective against most bacteria. It is not a question of whether or not natural medicines contain or contain effective antibiotics - since penicillins and cephalosporins are of mushroom origin, gramicidin S, streptomycin, tetracycline, erythromycin, chloramphenicol, and many other antibiotics are bacterial and synthetic antibiotics based on natural patterns. The question is when famous antibiotics are all natural, so why is herbal infection treatment so bad?
Why is the herbal treatment of infections so bad?
I say this is because the typical, casual, teaser approach of the herbalists and their patients, who is celebrating success in the treatment and prevention of non-infectious diseases, is absolutely inappropriate in the treatment of microbial infections . The major difference between infectious and noninfectious diseases is that the pathogens of the infections are subject to evolution. Fighting microbes resembles a warrior: A new weapon must defeat the enemy before it develops the weapon. And the evolution of microbes is very fast, so the healer has about 3 weeks of infection to kill the enemy - then (if he still lives) he can claim old weapons as obsolete and replace new ones. I say that in the treatment of infections, the soothing approach to the herbal industry must be replaced by the discipline of standardized pharmaceutical forms and strict dosingtypical for the use of antibiotics in Western medicine. When patients drink what they want, when they want and how much they want, it can not be surprising that shrimp and sage for the plague and chlamydia disease do not. Especially when the long generations of our healing ancestors have tried it for them ...
Plants with antibiotic and antiseptic effects
- Typical antimicrobial adaptogen is the purple chamois , which has traditionally been used in North America to treat infections and injuries. According to the Hudson2012ape overview, traditional thalamus indications include influenza , respiratory infections , toothache, urinary and sexually transmitted infections, ulcers, burns, skin infections, insect stings, allergiesand rheumatic fever. The same review refers to the presence of specific antibacterial and antiviral effects in this herb. In recent years, endophytic bacteria and fungus fungi that live within the plant's tissues (probably as nitrifying bacteria living inside the root of the legume) have been reported to be at least part of its antibiotic effects ( Maida2016aib , Carvalho2016mpd ).
- Baikal Shihak is valuable for its action against bacterial infections ( Bozov2015aan , Qian2015sbb ), in TČM it is used for the so-called "extinction of fever", ie practically for the treatment of respiratory infections , diarrhea and digestive disorders , hepatitis and jaundice .
- The Indian trumpet resembles a shell with its baykaline content and also has antimicrobial effects.
- Sage is an inseparable part of the traditional ranhojičství and treat infections, whether it is our sage , the Chinese sage červenokořenná revered TCM, American white sage revered Indian shamans, or other species ( Salvia hispanica , sage shrub , sage malolistá , Salvia chamaedryoides , S. wiedemannii , S multicaulis , S. austriaca , S. deserta , S. adenophora , S. verticcilata , etc., about sage-like wildlifenot to mention). Antibacterial properties do not exhaust the list of indications of the traditional panacea called sage, for example, the Su2015smt overview .
- The medical moon is another traditional weapon of European healers. An example of a modern experimental study of its antibiotic effects is Efstratiou2012aac .
- Zederach Indian is a tree with antibacterial properties, which is said to be harmless. Overview of Subapriya2005mpn focuses on the use of its leaves, the Komerm2013rpt overview of the properties of the so-called Nimbus oil obtained from the tree.
- The spider is another traditional antibacterial herb, the antibiotic component identifies, for example, Moricz2015tia . It is part of the Herbal Septiceb ( Eslami2012pes ) active in septic states.
- The antibacterial plant is also a nettle (Urtica dioica), see Motamedi2014iud .
- Nigella sativa has according Morsi2000aec activity against several strains of bacteria resistant to conventional antibiotics.
- According to the review of Muluye2014aae coming from TČM , the antibiotic effects also include dwarf bora , Viola philippica, Pulsatilla chinensis, Houttuynia cordata, and Poutatilla cordata .
- Other known antibacterial plants are cinnamon , clove , quinine, kazeput alternate ... We can not forget the antiseptic effects of garlic , onion and protective compounds of crucifers (horseradish, wasabi), shrimp, pepper, astrovite (chimpanzee, yarrow)
- Effective and especially popular in the past were simple disinfectants: phenol, camphor, benzoic acid (so called benzoic wood), alcohol, methanol, propanol, vinegar and other organic acids. In fact, citric acid serves as a protection in citrus fruits, the first barrier is limonene and other volatile substances of the bark.
When I talk about the absence of known strong antibiotic effects in common medicinal plants, it does not apply to medicinal sponges - since penicillin is also from mold. If you only focus on the classic mushroom ( Macromycota ), I came across an interesting Italian study ( Bianco1981bra ), which measured the antimicrobial effects in several dozen forest Basidiomycetes and effectiveness against Staphylococcus aureus found at křehutky brownish gray ( Psathyrella spadiceogrisea ) pstřeně oak ( Fistulina hepatica ) ( Fomitopsis pinicola ), edible tusk (Shitake , Lentinula edodes ) and fescue lice (Deconica coprophila ). Edelweed is easy to buy, all other mushrooms grow in our country, although I do not know how abundantly. If an enlightened forester or a living folk healer who would combine this combination of mushrooms and prepare the potion appropriately, this potion would probably take on the gold staphylococcus. Note: Fossil lice are among the non-hallucinogenic lyes, so we do not have to worry about it in this way if we move over the nature of what is usually growing. Finally, I would also like to mention that some antibiotic properties against gold staphylococcus have aplanoxic acids and gloss glossy triterpenoids (see, for example, SmaniaJunior2006ddn ), but I do not see their pharmacodynamics or the dose at which the antibiotic effects might be apparent.
Principles of effective use of natural antibiotics in treatment
Publication and popularization of such lists of effective plants is of great importance in non-infectious diseases, but in the fight against microbial diseases, it is more necessary to have standardized pharmaceutical forms derived from these herbs or better from their particular active ingredients . I'm sorry that I have to play cards in the rotten pharmaceutical industry here, but the fight against infection can not be resolved differently. It is aesthetic to use herbs in natural form (roots, teas, etc.), but in combating infection it is necessary to guarantee the content of antibiotic substances and their disciplined use. It is a challenge and a question for the pharmaceutical industry why there are no tablets of the Echinacea antibiotic tablets or "Salvianolic acid B" tablets against Neisseria meningitidis causing inflammation of the brain skins as it suggestsHuttunen2016nap or exactly standardized "sage diterpene" tablets with a list of susceptible strains of bacteria and recommended dosing as identified by the experimental Bisio2017ahd study . Since sage had been used by innumerable generations of our ancestors, it would not be too much surprise for the bacilli in the war of infection. However, the disciplined use of its active substances could alleviate the course of bacterial infections and supplement the treatment with conventional fungal and bacterial antibiotics.
The doctors do the herbs quite daintily
Here I have to highlight the approach of the TCM, which does not deliver the herbs in the Czech Republic, but it is in the form of an exact prescription, usually the herbal powder prescribed for a particular patient who has to use it regularly three times a day. Only in this way can the antibacterial and antibiotic effects of herbs benefit. Do not use herbs to treat infectious diseases yourself - just to boost pathogens. Go to the TCM Center or to a conscious MUDr. physicians familiar with medical botany.