Cholinergic effects adaptogens - effect on memory
Many adaptogens have protective effects on the CNS . This has also led to research their effect on memory protection, which in turn is associated with the cholinergic system.
Ginseng ( Nitta1995pge ) and American ginseng ( Sloley1999age ) regulate scopolamine impaired learning in rats. This effect was attributed specifically ginsenosides Rg 1 ( Yamaguchi1995egi ) and ginsenosides Rb 1 ( benishin1991egr ), who allegedly also facilitates an outpouring of acetylcholine from the hippocampus. According Salim1997grr also ginsenoside Rb 1 zyvšuje expression of enzymes and transporters acetylcholine transmission - mRNA acetylransferázy choline and the like. Conflicting reports regarding gssd. Rb 1 gives Yamaguchi1996egi by which memory protects gssd. R 1 and R , but not gssd Rb 1 , Rd , F 2 , Rf , Rh 1 or 20-O-Glu-PPD . Gssd Rg 2 , Rg 3 , compound K and aglycon protopanaxatriol reversibly block the neuronal acetylcholine nicotinic receptor α3β4. ( Lee2003deb , Jeong2004sgr , Lee2009rlr ).